莱昂内尔Cheruzel

Light-Driven Biocatalysts and their Activation

莱昂内尔Cheruzel is looking to expand the toolbox of organic chemistry reactions. 他的 research is centered around the use of hybrid P450 biocatalysts and their activation by visible light to produce chemicals that are difficult to obtain using traditional 方法. In the last two decades, biocatalysis has emerged as an important technology in the production of pharmaceuticals, flavors, fragrances, and beyond.

“Ultimately,” he says, “this work will find applications in the economically and environmentally friendly synthesis of new chemical compounds and potential drugs.”

Developing new synthetic routes has been made possible through Cheruzel’s work combining chemical catalysis with the lightdriven biocatalysis. Cheruzel’s credits his postdoctoral 导师哈里·B. Gray at Caltech, for instilling in him a passion for chemistry. “He had such an impact on me both personally and intellectually,” he says.

Cheruzel himself has supervised more than 130 undergraduate and graduate students in the lab since joining 菠菜网lol正规平台 in 2009. 他的 students have g一个 on to great success, working for companies including Boehringer Ingelheim, Cytokinetics, and Genentech, 攻读博士学位.D. degrees at UC Berkeley, UC San Francisco, UC Santa Cruz, University of Illinois Urbana-Champaign, and University of Michigan.

“Watching students develop as scientists and succeed in their endeavors has been personally rewarding and continues to motivate my mentoring efforts.”

布丽姬特佛利, ’20 Chemistry, uses the automated pipeting and dispensing of a liquid-handling 系统.

Chemistry, College of 科学
Sponsors: National Institutes of Health, National 科学 Foundation

菠菜网lol正规平台 研究基金会 2019 年度报告